Risks of Serotonin Syndrome when Combining Psychedelics with Antidepressants

Board Certified Psychiatric Pharmacists Dr.’s Ben Malcolm and Kelan Thomas recently published a review article discussing the risks of serotonin syndrome with various serotonergic psychedelics, either alone or in combination with serotonergic antidepressants. In this article, the authors offer a short summary of their main findings.

Could Synthetic Mescaline Protect Declining Peyote Populations?

The rise in popularity of peyote has unfortunately led to overharvesting which consequently poses a great risk for the future of the species. With the increasing need to protect peyote, synthetic mescaline may offer an alternative gateway into this experience that is bereft of issues regarding sustainability. This article summarizes the chemical composition and production of synthetic mescaline.

Iboga Conservation

This articles highlights conservation issues around Tabernanthe iboga, sacred plant medicine of the Bwiti and a common source of ibogaine used in the treatment of addictions.

When Ayahuasca Microdosing Might Cause Serotonin Toxicity

While there has been promising evidence of safety and effectiveness for ayahuasca macrodosing to treat depression, the medical risks and benefits of ayahuasca microdosing...

The Scientific Study of Ayahuasca Ethno-Varieties with Regina Célia de Oliveira

Jasmine Virdi interviews Regina Célia de Oliveira, a Brazilian biologist and professor at Brasília University, specializing in the study of Banisteriopsis caapi and other plants that make up the ayahuasca brew. In this article, Regina shares about the different varieties of the B. caapi vine, the deeply sophisticated knowledge of traditional peoples about these vines, and the importance of protecting these plant species amidst ongoing ecological destruction in the Amazon Rainfor-est.

Toad Conservation

There is an alarming global decline in lncilus alvarius toad populations, the toads who secrete 5-MeO-DMT, because of multiple ecological reasons and the increased interest in toad ‘milking’ for psychedelic experiences. Anya Ermakova, Ph.D. educates the reader on the ecological impacts of these toad populations and provides alternative, synthetic options for psychonauts who would like to use 5-MeO-DMT.

20 Best Books About Peyote and Mescaline

Anya Ermakova, Ph.D compiled a list of the 20 best books about peyote and mescaline. These non-fiction books about Lophophora williamsii are written by scholars of history, anthropology, religion, biology, and ecology and conservation.

Ayahuasca, Severe Illnesses, and the Mystery of Death

When someone is diagnosed with a severe, life-threatening illness, the affected individual may begin to ask several existential questions. The author, Lucas Maia, PhD, summarizes his findings from his doctoral thesis which studied the ritual use of ayahuasca and its therapeutic potential for those facing and fearing death.

Psychedelic Illusions are Not Pathological, and May Even Help You See...

This article summarizes psychiatric and neuroscientific findings on the similarities between psychedelic and psychiatric hallucinations.

Psychedelic Science Shies Away from Mysticism Without Losing Its Tenderness

The labeling of the psychedelic experience as ‘mystical’ may do little to improve public opinion about psychedelics, especially among those with traditional, conservative values. While it is no surprise that psychedelics can induce deep spiritual experiences, there is no scientific evidence that psychedelics can change one’s political or religious beliefs.