Neuroscientist Dráulio de Araújo leads clinical trials to gauge the antidepressant potential of DMT, but is also keen on deciphering why this psychedelic compound abounds in the jurema tree and all over the natural world.

Reporter recounts his experience as a volunteer in a Brazilian study that investigates the antidepressant potential of a psychedelic substance extracted from a tree native to the semi-arid Caatinga Region.

This is an anonymous letter by members of the Union of the Vegetal (UDV) showing their dissatisfaction with the explicit support of certain masters at the top of the hierarchy of the UDV for the Bolsonaro government's denialist and anti-democratic policy, claiming that these practices are completely out of line with the teachings of Mestre Gabriel. Conservative demonstrations by the group's leaders are nothing new, but they began to gain public notoriety with the increase in political polarization in Brazil.

In an anonymous letter, members of the Union of the Vegetal (UDV) have shown their dissatisfaction with the explicit support of certain masters at the top of the hierarchy of the UDV for the Bolsonaro government's denialist and anti-democratic policy, claiming that these practices are completely out of line with the teachings of Mestre Gabriel. Conservative demonstrations by the group's leaders are nothing new, but they began to gain public notoriety with the increase in political polarization in Brazil.

The mystical experience is likely one of the therapeutic mechanisms for psychedelics, including ayahuasca, to have therapeutic potential for drug addiction. This article explores the findings of a study in which there was a connection between ayahuasca use and smoking cessation.

Jasmine Virdi and Oriana Mayorga explore the emergent field of psychedelic chaplaincy, exploring the ways in which spiritual and religious experiences are understood within the contemporary psychedelic landscape.

This brief and powerful history of Indigenous practices with ayahuasca before its globalization emphasizes the loss that has (and continues) to occur within these Indigenous communities. It also remarks on the importance of honoring and including Indigenous voices in the conversations being had as ayahuasca and other plant medicines gain popularity within the Western scientific sphere.

This article explores a paper written by Eduardo Ekman Schenberg and Konstantin Gerber titled Overcoming epistemic injustices in the biomedical study of ayahuasca: Towards ethical and sustainable regulation. While the paper promised to explore ways of overcoming these epistemic injustices and raises important issues, the author shares vast criticism due to its many controversial and inaccurate points.

In this feature, Glenn H. Shepard Jr. provides a colorful, detailed account of his experience in the Amazon with Matsigenka shamans of Peru, whom have a strong relationship with tobacco and hummingbirds. Through this journey, there was much to learn about Matsigenka practices and beliefs and the lessons that come with having these spiritual experiences.

This essay explores the relatonship between the recent boom in DIY (do-it-yourself) mushroom growing and the use of psychedelic mushrooms as both these topics become more mainstream.